SCHEMBL25768908

SCHEMBL25768908

c1ccc(-c2ccc(-c3cc(-c4ccc(-c5cc(-c6ccncc6)nc(-c6ccncc6)n5)cc4)cc(-n4c5ccccc5c5ccccc54)c3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.43
▸ KMT2A Q03164 7/20 0.43
▸ MEN1 O00255 6/20 0.43
▸ ALDH1A1 P00352 4/20 0.43
▸ HPGD P15428 3/20 0.43
▸ NTSR1 P30989 1/20 0.43
▸ DHODH Q02127 1/20 0.43
▸ HSP90AA1 P07900 1/20 0.40
▸ KDM4E B2RXH2 4/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ NFKB2 Q00653 1/20 0.40
▸ RELA Q04206 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ NPSR1 Q6W5P4 2/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25768878 1.00 MAPT (0.43) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL25768905 1.00 MAPT (0.43) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL25768880 1.00 MAPT (0.43) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL25768849 0.97 DHODH (0.41) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL25768911 0.97 DHODH (0.41) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL19397662 0.95 KMT2A (0.43) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL17853622 0.95 KMT2A (0.43) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL19397660 0.95 KMT2A (0.43) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL25768835 0.95 DHODH (0.42) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL25768831 0.95 DHODH (0.42) MAPTKMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255078-A1 Light Emitting Display Device LG DISPLAY CO., LTD. (KR) 2023-08-10 — — US disclosed
US-20230255078-A1 Light Emitting Display Device LG DISPLAY CO., LTD. (KR) 2023-08-10 — — US disclosed
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217815-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217815-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
EP-4207995-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG Display Co., Ltd. (KR) 2023-07-05 — — EP disclosed
EP-4207994-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG Display Co., Ltd. (KR) 2023-07-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same DBH, PRPH, NBAS MAPT 273/4885KMT2A 3578/4885MEN1 2680/4885
US-20230255078-A1 Light Emitting Display Device ITGAL, MAP1LC3C, ITGB4 MAPT 158/4885KMT2A 3248/4885MEN1 3420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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