SCHEMBL25768928

SCHEMBL25768928

c1ccc(-c2cc(-c3ccc(-c4cc(-c5ccncc5)nc(-c5ccncc5)c4)cc3)cc(-n3c4ccccc4c4ccccc43)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.45
▸ CYP19A1 P11511 1/20 0.44
▸ KMT2A Q03164 4/20 0.42
▸ MAPT P10636 3/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ HSP90AA1 P07900 1/20 0.42
▸ KDM4E B2RXH2 4/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ HPGD P15428 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ NOTUM Q6P988 1/20 0.41
▸ MAPK1 P28482 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ RECQL P46063 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ GSK3B P49841 1/20 0.39
▸ CDC7 O00311 1/20 0.39
▸ SQOR Q9Y6N5 1/20 0.38
▸ AR P10275 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25768930 1.00 DHODH (0.45) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL26235800 0.97 DHODH (0.43) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL25768933 0.97 DHODH (0.43) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL25768822 0.94 DHODH (0.44) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL25768824 0.94 DHODH (0.44) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL17691577 0.93 KDM4E (0.42) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL14425616 0.93 L3MBTL1 (0.47) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL14425603 0.93 L3MBTL1 (0.47) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL21973999 0.93 L3MBTL1 (0.47) DHODHCYP19A1KMT2AMAPTMEN1
SCHEMBL14425612 0.93 L3MBTL1 (0.47) DHODHCYP19A1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255078-A1 Light Emitting Display Device LG DISPLAY CO., LTD. (KR) 2023-08-10 — — US disclosed
US-20230255078-A1 Light Emitting Display Device LG DISPLAY CO., LTD. (KR) 2023-08-10 — — US disclosed
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217815-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
US-20230217815-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-07-06 — — US disclosed
EP-4207995-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG Display Co., Ltd. (KR) 2023-07-05 — — EP disclosed
EP-4207994-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY INCLUDING THE SAME LG Display Co., Ltd. (KR) 2023-07-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217821-A1 Light Emitting Device and Light Emitting Display Device Including the Same DBH, PRPH, NBAS DHODH 860/4885CYP19A1 2218/4885KMT2A 3578/4885
US-20230255078-A1 Light Emitting Display Device ITGAL, MAP1LC3C, ITGB4 DHODH 2913/4885CYP19A1 3072/4885KMT2A 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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