SCHEMBL25771349

SCHEMBL25771349

CCCCCCCCCCCCCCCCOCCCOP(=O)(O)OC[C@]1(C)CC[C@H](c2ccc3c(N)ncnn23)O1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.41
▸ FGFR1 P11362 3/20 0.37
▸ CYP3A4 P08684 4/20 0.35
▸ CYP2D6 P10635 4/20 0.35
▸ P2RY10 O00398 1/20 0.33
▸ S1PR3 Q99500 1/20 0.33
▸ ADK P55263 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077109 1.00 POLRMT (0.41) POLRMTFGFR1CYP3A4CYP2D6P2RY10
SCHEMBL25766615 0.98 POLRMT (0.42) POLRMTFGFR1CYP3A4CYP2D6S1PR3
SCHEMBL25770236 0.98 POLRMT (0.42) POLRMTFGFR1CYP3A4CYP2D6S1PR3
SCHEMBL25766720 0.88 POLRMT (0.39) POLRMTFGFR1CYP3A4CYP2D6P2RY10
SCHEMBL25770214 0.88 POLRMT (0.39) POLRMTFGFR1CYP3A4CYP2D6P2RY10
SCHEMBL25077197 0.88 POLRMT (0.43) POLRMTFGFR1CYP3A4CYP2D6P2RY10
SCHEMBL25077291 0.86 POLRMT (0.45) POLRMTFGFR1CYP3A4CYP2D6S1PR3
SCHEMBL25077145 0.85 POLRMT (0.41) POLRMTFGFR1CYP3A4CYP2D6S1PR3
SCHEMBL25770198 0.85 POLRMT (0.41) POLRMTFGFR1CYP3A4CYP2D6S1PR3
SCHEMBL25768624 0.85 POLRMT (0.41) POLRMTFGFR1CYP3A4CYP2D6S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212199-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. 2023-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212199-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PHOSPHO1, SGMS1, SGMS2 POLRMT 266/4885FGFR1 4854/4885CYP3A4 2080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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