Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 6/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26285621 | 0.88 | POLRMT (0.51) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25077210 | 0.88 | POLRMT (0.51) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25771349 | 0.86 | POLRMT (0.41) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25077109 | 0.86 | POLRMT (0.41) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25077197 | 0.85 | POLRMT (0.43) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25770236 | 0.84 | POLRMT (0.42) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25766615 | 0.84 | POLRMT (0.42) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25077212 | 0.82 | POLRMT (0.49) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL26276093 | 0.82 | POLRMT (0.49) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25076958 | 0.82 | POLRMT (0.36) | POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023527-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-02-23 | — | — | WO | disclosed |