Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176588 | 0.76 | CNR2 (0.53) | CNR2NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL14089571 | 0.76 | CNR2 (0.47) | CNR2NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL13011108 | 0.75 | CNR2 (0.59) | CNR2NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL13011106 | 0.75 | CNR2 (0.59) | CNR2NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL13545838 | 0.75 | RAB9A (0.54) | CNR2NPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13545753 | 0.75 | ALDH1A1 (0.69) | NPC1SMN1; SMN2RAB9ATSHRKMT2A | |
| SCHEMBL13545792 | 0.75 | ALDH1A1 (0.69) | NPC1SMN1; SMN2RAB9ATSHRKMT2A | |
| SCHEMBL13545827 | 0.75 | ALDH1A1 (0.69) | NPC1SMN1; SMN2RAB9ATSHRKMT2A | |
| SCHEMBL13011091 | 0.74 | CNR2 (0.98) | CNR2NPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13011110 | 0.74 | CNR2 (0.98) | CNR2NPC1SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | disclosed |