Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 8/20 | 0.42 |
| ▸ | DRD5 | P21918 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3440776 | 0.81 | MAPT (0.39) | DRD2HTR2AHTR1ANR1H2DRD1 | |
| Hydrochloric Acid SCHEMBL11476937 | 0.79 | DRD2 (0.51) | DRD2DRD1DRD5DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7506644 | 0.78 | MAPT (0.39) | DRD2HTR2AHTR1ANR1H2KDM4E | |
| SCHEMBL17662597 | 0.77 | DRD2 (0.55) | DRD2HTR1ADRD1DRD5DRD3 | |
| SCHEMBL19121066 | 0.77 | DRD2 (0.55) | DRD2HTR1ADRD1DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL11457319 | 0.76 | DRD2 (0.54) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL216418 | 0.76 | DRD1 (0.51) | DRD2NR1H2DRD1DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL11458075 | 0.75 | DRD2 (0.54) | DRD2HTR1ADRD1DRD5DRD3 | |
| SCHEMBL4752284 | 0.75 | MAOA (0.56) | DRD2HTR2AHTR1ADRD1DRD5 | |
| SCHEMBL3950020 | 0.75 | MAOA (0.56) | DRD2HTR2AHTR1ADRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B9 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |