Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 7/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | DRD1 | P21728 | 6/20 | 0.49 |
| ▸ | DRD5 | P21918 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950020 | 1.00 | MAOA (0.56) | MAOADRD2HTR1AHTR2ADRD1 | |
| Bromide SCHEMBL3440715 | 0.98 | MAOA (0.54) | MAOADRD2HTR1AHTR2ADRD1 | |
| SCHEMBL7655001 | 0.86 | MAOA (0.56) | MAOADRD2HTR1AHTR2ADRD1 | |
| SCHEMBL29557733 | 0.86 | MAOA (0.56) | MAOADRD2HTR1AHTR2ADRD1 | |
| Hydrochloric Acid SCHEMBL7513323 | 0.85 | MAOA (0.54) | MAOADRD2HTR1AHTR2ADRD1 | |
| SCHEMBL8011243 | 0.79 | MAOA (0.56) | MAOADRD2HTR1AHTR2APLAU | |
| SCHEMBL8032013 | 0.79 | MAOA (0.56) | MAOADRD2HTR1AHTR2AESR2 | |
| SCHEMBL21939319 | 0.78 | DRD2 (0.49) | MAOADRD2HTR1AHTR2ADRD1 | |
| SCHEMBL2276891 | 0.77 | DRD1 (0.56) | DRD2HTR1AHTR2ADRD1DRD5 | |
| SCHEMBL8024197 | 0.77 | MAOA (0.60) | MAOADRD2DRD1DRD5CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135525-A2 | SUBSTITUTED AZETIDINES, MANUFACTURING AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |