SCHEMBL25779082

SCHEMBL25779082

N#Cc1ccc(-c2csnc2C(=O)O)nc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
PIN1 Q13526 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
EGLN2 Q96KS0 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SCD5 Q86SK9 1/20 0.35
GRM5 P41594 3/20 0.34
MAP4K4 O95819 1/20 0.34
ATR Q13535 1/20 0.34
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
HTT P42858 1/20 0.33
TMPRSS4 Q9NRS4 1/20 0.33
P4HA1 P13674 1/20 0.33
P4HTM Q9NXG6 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM1A O60341 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25779087 0.81 TDP1 (0.40) TDP1PIN1KDM4CEGLN2MAP4K4
SCHEMBL25779085 0.80 SLC22A12 (0.43) TDP1EGLN2MEN1KMT2AMAP4K4
SCHEMBL25779267 0.78 PPARG (0.37) KDM4CEGLN2MEN1KMT2ASCD5
SCHEMBL25779094 0.75 KMO (0.38) TDP1KDM4C
SCHEMBL25778715 0.75 SCD5 (0.37) KDM4CEGLN2MEN1KMT2ASCD5
SCHEMBL25779078 0.74 TDP1 (0.41) TDP1SCD5MAP4K4
SCHEMBL25779102 0.73 KDM4E (0.49) KDM4CEGLN2MEN1KMT2ASCD5
SCHEMBL25778943 0.73 KDM4C (0.36) KDM4CEGLN2MEN1KMT2ASCD5
SCHEMBL31336729 0.73 HCRTR2 (0.40) KDM4CEGLN2SCD5GRM5KDM4E
SCHEMBL25779263 0.72 GRM5 (0.39) KDM4CEGLN2MEN1KMT2ASCD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118434-A1 PESTICIDALLY ACTIVE AMIDE COMPOUNDS GLOBACHEM NV (BE) 2023-06-29 WO disclosed