SCHEMBL25779263

SCHEMBL25779263

N#Cc1ccc(-c2nccnc2C(=O)O)nc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 4/20 0.39
KDM4C Q9H3R0 1/20 0.38
SLC22A12 Q96S37 1/20 0.38
EGLN2 Q96KS0 1/20 0.38
POLB P06746 1/20 0.37
P4HA1 P13674 1/20 0.36
P4HTM Q9NXG6 1/20 0.36
ATR Q13535 1/20 0.36
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
HTT P42858 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SCD5 Q86SK9 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22497920 0.87 ALDH1A1 (0.40) GRM5SLC22A12EGLN2POLBKDM4E
SCHEMBL30062517 0.87 PARP1 (0.40) GRM5SLC22A12EGLN2POLBATR
SCHEMBL29434535 0.87 ALDH1A1 (0.40) GRM5SLC22A12EGLN2POLBKDM4E
SCHEMBL25779268 0.81 POLB (0.37) KDM4CSLC22A12EGLN2POLBKDM4E
SCHEMBL25779260 0.80 SLC22A12 (0.49) SLC22A12EGLN2POLBATREGLN1
SCHEMBL25779267 0.75 PPARG (0.37) GRM5KDM4CSLC22A12EGLN2POLB
SCHEMBL25778736 0.75 GSK3B (0.42) GRM5KDM4CSLC22A12EGLN2P4HA1
SCHEMBL26422199 0.74 ALDH1A1 (0.44) GRM5EGLN2KDM4EALDH1A1HPGD
SCHEMBL25779102 0.74 KDM4E (0.49) GRM5KDM4CSLC22A12EGLN2P4HA1
SCHEMBL25782841 0.74 GRM5 (0.37) GRM5KDM4CSLC22A12EGLN2P4HA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118434-A1 PESTICIDALLY ACTIVE AMIDE COMPOUNDS GLOBACHEM NV (BE) 2023-06-29 WO disclosed