SCHEMBL22497920

SCHEMBL22497920

CC(=O)c1nccnc1-c1ccc(C#N)cn1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
MAPT P10636 1/20 0.40
GRM5 P41594 5/20 0.38
KDM4E B2RXH2 3/20 0.37
HPGD P15428 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
HTT P42858 1/20 0.37
SLC22A12 Q96S37 1/20 0.37
EGLN2 Q96KS0 1/20 0.37
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PPARG P37231 1/20 0.33
LRRK2 Q5S007 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434535 1.00 ALDH1A1 (0.40) ALDH1A1MAPTGRM5KDM4EHPGD
SCHEMBL25779263 0.87 GRM5 (0.39) ALDH1A1MAPTGRM5KDM4EHPGD
SCHEMBL30062517 0.85 PARP1 (0.40) ALDH1A1GRM5KDM4EHPGDL3MBTL1
SCHEMBL22510347 0.77 TGFBR1 (0.40) GRM5
SCHEMBL22498633 0.77 PTK2 (0.42) L3MBTL1KMT2A
SCHEMBL22498649 0.77 HDAC3 (0.34) ALDH1A1MAPTKDM4E
SCHEMBL29659802 0.77 TGFBR1 (0.40) GRM5
SCHEMBL29659853 0.77 PTK2 (0.42) L3MBTL1KMT2A
SCHEMBL22510346 0.77 ALDH1A1 (0.40) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL29659808 0.77 ALDH1A1 (0.40) ALDH1A1MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4643644-A2 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS Syngenta Crop Protection AG (CH) 2025-11-05 EP disclosed
EP-4051673-B1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-09-24 EP disclosed
EP-3947358-B1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-06-18 EP disclosed
US-12281095-B2 Pesticidally active diazine-amide compounds SYNGENTA CROP PROTECTION AG (CH) 2025-04-22 US disclosed
US-20230131903-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US disclosed
US-20230131903-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US disclosed
US-20230131903-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US disclosed
US-20230002359-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-05 US disclosed
US-20230002359-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-05 US disclosed
US-20220185789-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-06-16 US disclosed
US-20220169629-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US disclosed
US-20220169629-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US disclosed
EP-3953343-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
EP-3947358-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS Syngenta Crop Protection AG (CH) 2022-02-09 EP disclosed
CN-113677672-A Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2021-11-19 CN disclosed
CN-113631549-A Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2021-11-09 CN disclosed
WO-2020208036-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO disclosed
WO-2020208036-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO disclosed
WO-2020201079-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 WO disclosed
WO-2020201079-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131903-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS DDT, ACHE, GSTO1 ALDH1A1 922/4885MAPT 194/4885GRM5 1872/4885
US-20220185789-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS DDT, ACHE, NIT2 ALDH1A1 787/4885MAPT 674/4885GRM5 2029/4885
US-12281095-B2 Pesticidally active diazine-amide compounds DDT, ACHE, NIT2 ALDH1A1 787/4885MAPT 674/4885GRM5 2029/4885
US-20230002359-A1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS DDT, ACHE, GSTO1 ALDH1A1 746/4885MAPT 283/4885GRM5 1869/4885
US-20220169629-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS DDT, ACHE, NIT2 ALDH1A1 1134/4885MAPT 569/4885GRM5 1856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.