SCHEMBL25782841

SCHEMBL25782841

N#Cc1ccc(-c2ncoc2C(=O)O)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 5/20 0.37
EGLN2 Q96KS0 1/20 0.36
SCD5 Q86SK9 1/20 0.35
XDH P47989 1/20 0.34
SLC22A12 Q96S37 1/20 0.34
P4HA1 P13674 1/20 0.34
P4HTM Q9NXG6 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
KCNH2 Q12809 1/20 0.34
GSK3B P49841 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
MAP4K4 O95819 1/20 0.33
ATR Q13535 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25778736 0.78 GSK3B (0.42) GRM5EGLN2SCD5XDHSLC22A12
SCHEMBL25778706 0.74 MAP4K4 (0.38) GRM5EGLN2SCD5SLC22A12P4HA1
SCHEMBL25779263 0.74 GRM5 (0.39) GRM5EGLN2SCD5SLC22A12P4HA1
SCHEMBL25778938 0.73 GRM5 (0.38) GRM5EGLN2SCD5P4HA1P4HTM
SCHEMBL25779075 0.71 KDM4E (0.39) GRM5EGLN2SCD5XDHSLC22A12
SCHEMBL25778704 0.71 KDM4E (0.46) P4HTMKDM4EL3MBTL1KDM4CKMT2A
SCHEMBL25779267 0.70 PPARG (0.37) GRM5EGLN2SCD5XDHSLC22A12
SCHEMBL6662295 0.70 LDHA (0.56) EGLN2SLC22A12P4HA1P4HTMKDM4E
SCHEMBL995794 0.70 GRM5 (0.54) GRM5EGLN2KDM4EALDH1A1HPGD
SCHEMBL31172969 0.70 GRM5 (0.54) GRM5EGLN2KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118434-A1 PESTICIDALLY ACTIVE AMIDE COMPOUNDS GLOBACHEM NV (BE) 2023-06-29 WO disclosed