SCHEMBL25779677

SCHEMBL25779677

CC(O)(COC(=O)C1CC2C=CC1C2)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.44
RAB9A P51151 1/20 0.44
HPGD P15428 1/20 0.42
POLB P06746 3/20 0.41
KMT2A Q03164 3/20 0.41
HSD17B10 Q99714 2/20 0.40
APEX1 P27695 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
ESR2 Q92731 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPK1 P28482 2/20 0.36
MAPT P10636 1/20 0.34
MEN1 O00255 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2342682 0.90 ALDH1A1 (0.41) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL14410083 0.86 ALDH1A1 (0.45) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL950161 0.86 ALDH1A1 (0.45) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL5872995 0.85 ALDH1A1 (0.45) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL14133965 0.84 ALDH1A1 (0.44) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL12228709 0.84 ALDH1A1 (0.46) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL145490 0.84 ALDH1A1 (0.46) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL23228322 0.84 ALDH1A1 (0.46) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL4400475 0.84 ALDH1A1 (0.46) ALDH1A1RAB9AHPGDPOLBKMT2A
SCHEMBL14449005 0.84 ALDH1A1 (0.46) ALDH1A1RAB9AHPGDPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230213862-A1 PHOTORESIST COMPOSITIONS AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-07-06 US disclosed