SCHEMBL4400475

SCHEMBL4400475

CC(C)(COC(=O)C1CC2C=CC1C2)COC(=O)C1CC2C=CC1C2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.46
HPGD P15428 1/20 0.46
POLB P06746 3/20 0.45
KMT2A Q03164 3/20 0.45
RAB9A P51151 1/20 0.45
LMNA P02545 2/20 0.45
KDM4E B2RXH2 2/20 0.45
HSD17B10 Q99714 2/20 0.43
APEX1 P27695 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
ESR2 Q92731 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAPK1 P28482 2/20 0.39
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14449005 1.00 ALDH1A1 (0.46) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL14449932 1.00 ALDH1A1 (0.46) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL24255192 0.94 ALDH1A1 (0.43) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL24375932 0.93 ALDH1A1 (0.42) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL12228740 0.90 ALDH1A1 (0.46) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL23228322 0.90 ALDH1A1 (0.46) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL7195578 0.90 ALDH1A1 (0.44) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL5872995 0.89 ALDH1A1 (0.45) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL14435506 0.87 LMNA (0.47) ALDH1A1HPGDPOLBKMT2ARAB9A
SCHEMBL899899 0.87 LMNA (0.47) ALDH1A1HPGDPOLBKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018298-A1 OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS ExxonMobil Product Solutions Company 2024-01-18 US disclosed
US-20240018298-A1 OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS ExxonMobil Product Solutions Company 2024-01-18 US disclosed
US-20230174708-A1 NORBORNENE ESTERS AS COMONOMERS FOR THERMOSET ARTICLES ExxonMobil Product Solutions Company 2023-06-08 US disclosed
US-20230174708-A1 NORBORNENE ESTERS AS COMONOMERS FOR THERMOSET ARTICLES ExxonMobil Product Solutions Company 2023-06-08 US disclosed
WO-2023049857-A1 HYBRID COMPOSITIONS COMPRISING OLEFINIC COMPOSITIONS AND RESIN COMPOSITIONS POLYMERIZABLE BY ADDITION OR CONDENSATION POLYMERIZATION REACTIONS MATERIA, INC. (US) 2023-03-30 WO disclosed
US-20220127491-A1 COATING COMPOSITIONS ExxonMobil Product Solutions Company 2022-04-28 US disclosed
WO-2022036044-A1 OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS MATERIA, INC. (US) 2022-02-17 WO disclosed
WO-2020123946-A1 COATING COMPOSITIONS MATERIA, INC. (US) 2020-06-18 WO disclosed
EP-2094760-B1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD 3M INNOVATIVE PROPERTIES CO (US) 2017-05-31 EP disclosed
US-8431625-B2 Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-30 US disclosed
US-8431625-B2 Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-30 US disclosed
US-8178604-B2 Solid materials obtainable by ring-opening metathesis polymerization 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
US-8178604-B2 Solid materials obtainable by ring-opening metathesis polymerization 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
EP-1815838-B1 Solid materials obtainable by the ring-opening methathesis polymerization 3M INNOVATIVE PROPERTIES CO (US) 2010-09-08 EP disclosed
US-20100036015-A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD 3M INNOVATIVE PROPERTIES COMPANY 2010-02-11 US disclosed
US-20100036015-A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD 3M INNOVATIVE PROPERTIES COMPANY 2010-02-11 US disclosed
US-20090088494-A1 SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION 3M INNOVATIVE PROPERTIES COMPANY 2009-04-02 US disclosed
US-20090088494-A1 SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION 3M INNOVATIVE PROPERTIES COMPANY 2009-04-02 US disclosed
WO-2008077001-A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-06-26 WO disclosed
WO-2007089801-A1 SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-08-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100036015-A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD DNMT3B, HMBS, MMAB ALDH1A1 454/4885HPGD 463/4885POLB 65/4885
US-20090088494-A1 SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION MMAB, DNMT3B, RHEB ALDH1A1 4132/4885HPGD 3718/4885POLB 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.