Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.56 |
| ▸ | BRD4 | O60885 | 4/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | IL1B | P01584 | 1/20 | 0.48 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.48 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25782017 | 0.91 | CRBN (0.52) | CRBNBRD4STAT3TNFIL1B | |
| SCHEMBL25031878 | 0.89 | STAT3 (0.53) | CRBNBRD4STAT3MAP1LC3B | |
| SCHEMBL25770457 | 0.88 | CRBN (0.51) | CRBNBRD4STAT3MAP1LC3B | |
| SCHEMBL25830051 | 0.88 | CRBN (0.52) | CRBNBRD4STAT3TNFIL1B | |
| SCHEMBL25031967 | 0.86 | CRBN (0.51) | CRBNBRD4STAT3DDB1 | |
| SCHEMBL805995 | 0.85 | CRBN (0.60) | CRBNBRD4TNFIL1BIKZF1 | |
| SCHEMBL24068298 | 0.85 | STAT3 (0.52) | CRBNBRD4STAT3DDB1 | |
| SCHEMBL25032419 | 0.85 | CRBN (0.55) | CRBNBRD4STAT3TNFIL1B | |
| SCHEMBL22252682 | 0.85 | CRBN (0.55) | CRBNBRD4STAT3TNFIL1B | |
| SCHEMBL19764202 | 0.85 | CRBN (0.59) | CRBNBRD4TNFIL1BIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | CRBN 286/4885BRD4 1230/4885STAT3 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.