Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CBFB | Q13951 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23836107 | 0.86 | MAOB (0.55) | MAOBADORA2AHPSEHPGDSALDH1A1 | |
| SCHEMBL6952303 | 0.84 | MAOB (0.54) | MAOBADORA2AHPSEALDH1A1SMN1; SMN2 | |
| SCHEMBL30402898 | 0.84 | MAOB (0.58) | MAOBADORA2AHPSEALDH1A1SMN1; SMN2 | |
| SCHEMBL11738344 | 0.82 | MAOB (0.53) | MAOBADORA2AHPSEALDH1A1SMN1; SMN2 | |
| SCHEMBL7475827 | 0.82 | PKN1 (0.57) | PARP1PKN1PKN2KDM4EKMT2A | |
| SCHEMBL7427217 | 0.81 | HRH4 (0.56) | HPSEALDH1A1SMN1; SMN2HSD17B10TP53 | |
| SCHEMBL24740174 | 0.80 | MAOB (0.51) | MAOBADORA2AHPSEALDH1A1SMN1; SMN2 | |
| SCHEMBL23835766 | 0.80 | MAOB (0.51) | MAOBADORA2AHPSEALDH1A1SMN1; SMN2 | |
| SCHEMBL7422467 | 0.78 | KDM4E (0.54) | HPGDPARP1PKN1PKN2CNR2 | |
| SCHEMBL24112861 | 0.76 | PKN1 (0.40) | MAOBADORA2AHPGDSSMN1; SMN2PKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | MAOB 1780/4885ADORA2A 4145/4885HPSE 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.