SCHEMBL25787463

SCHEMBL25787463

CCC(C)(C)n1c2c(-c3ccccc3)cccc2c2cccc(-c3ccccc3)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39
KDM4E B2RXH2 3/20 0.36
RCE1 Q9Y256 2/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
BRD4 O60885 1/20 0.35
CRHR1 P34998 1/20 0.35
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
GAA P10253 1/20 0.34
MAP4K4 O95819 1/20 0.33
CSF1R P07333 1/20 0.33
FGFR1 P11362 1/20 0.33
PDGFRA P16234 1/20 0.33
LTK P29376 1/20 0.33
KDR P35968 1/20 0.33
MAPK8 P45983 1/20 0.33
CSNK1A1 P48729 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14929538 0.84 PDCD1 (0.39) PDCD1CD274PPARGPPARAKDM4E
SCHEMBL21077138 0.80 PDCD1 (0.43) PDCD1CD274KDM4ERCE1BRD4
SCHEMBL22853003 0.78 ALKBH5 (0.39) PDCD1CD274PPARGPPARAKDM4E
SCHEMBL25697003 0.77 SOAT1 (0.37) KDM4ECNR1CNR2
SCHEMBL27900579 0.75 KDM4E (0.49) KDM4ERCE1CYP2C19ALDH1A1POLB
SCHEMBL25138010 0.74 CNR2 (0.43) CNR1CNR2ALDH1A1ENPP1HPGD
SCHEMBL14931060 0.74 HSD17B10 (0.46) PDCD1CD274BRD4MAP4K4CSF1R
SCHEMBL25696990 0.73 KDM4E (0.39) KDM4ECNR1CNR2ALDH1A1
SCHEMBL6280030 0.72 KDM4E (0.50) KDM4ERCE1CNR1CNR2GAA
SCHEMBL24775134 0.72 HSD17B10 (0.37) PDCD1CD274KDM4EABCG2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRM1, OPRD1, OXER1 PDCD1 292/4885CD274 121/4885PPARG 1487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.