Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 7/20 | 1.00 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | STAMBP | O95630 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25787747 | 0.90 | NNMT (1.00) | NNMTPIK3C3GRM5ASIC3SMN1; SMN2 | |
| SCHEMBL1680658 | 0.85 | NNMT (0.73) | NNMTPIK3C3GRM5ASIC3ABL1 | |
| SCHEMBL10293369 | 0.82 | NNMT (0.69) | NNMTPIK3C3ASIC3ABL1PIK3CD | |
| SCHEMBL17173795 | 0.81 | NNMT (0.68) | NNMTPIK3C3GRM5ASIC3ABL1 | |
| SCHEMBL13332908 | 0.80 | NNMT (0.66) | NNMTPIK3C3GRM5ASIC3ABL1 | |
| SCHEMBL25787975 | 0.79 | NNMT (0.66) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL8389605 | 0.79 | NNMT (0.64) | NNMTPIK3C3ASIC3ABL1ALOX5AP | |
| SCHEMBL12960636 | 0.77 | NNMT (0.62) | NNMTPIK3C3GRM5ASIC3ABL1 | |
| SCHEMBL25787851 | 0.76 | NNMT (0.62) | NNMTGRM5ALOX5APFEN1CHRNB2 | |
| SCHEMBL22226403 | 0.76 | NNMT (0.61) | NNMTPIK3C3GRM5CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129512-A1 | BICYCLIC INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE, COMPOSITIONS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-07-06 | — | — | WO | disclosed |