Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU2 | Q9Y3R4 | 2/20 | 0.34 |
| ▸ | NEU4 | Q8WWR8 | 1/20 | 0.34 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15662367 | 0.79 | NEU2 (0.38) | NEU2NEU4NEU3 | |
| SCHEMBL29116406 | 0.79 | NEU2 (0.38) | NEU2NEU4NEU3 | |
| SCHEMBL15658717 | 0.79 | NEU2 (0.38) | NEU2NEU4NEU3 | |
| SCHEMBL15879687 | 0.77 | LMNA (0.33) | NEU2NEU4NEU3 | |
| SCHEMBL28366315 | 0.77 | LMNA (0.33) | NEU2NEU4NEU3 | |
| SCHEMBL18902766 | 0.74 | HIF1A (0.36) | — | |
| SCHEMBL19171896 | 0.74 | HIF1A (0.36) | — | |
| SCHEMBL13868638 | 0.74 | PDE4A (0.56) | — | |
| SCHEMBL13572033 | 0.74 | PDE4A (0.56) | — | |
| SCHEMBL13359968 | 0.74 | PDE4A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212216-A1 | SYNTHESIS OF LACTONE DERIVATIVES AND THEIR USE IN THE MODIFICATION OF PROTEINS | GENIE BIOTECH UK LTD. (GB) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212216-A1 | SYNTHESIS OF LACTONE DERIVATIVES AND THEIR USE IN THE MODIFICATION OF PROTEINS | AGL, PGLS, DDOST | NEU2 1271/4885NEU4 867/4885NEU3 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.