Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | FPR3 | P25089 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29542631 | 0.83 | ALDH1A1 (0.57) | KMT2AALDH1A1NPSR1HTTMEN1 | |
| SCHEMBL2450444 | 0.83 | MC4R (0.58) | KMT2AALDH1A1TAAR1L3MBTL1MEN1 | |
| SCHEMBL14813679 | 0.83 | MC4R (0.58) | KMT2AALDH1A1TAAR1L3MBTL1MEN1 | |
| SCHEMBL21540802 | 0.81 | CTSC (0.56) | KMT2AMEN1 | |
| SCHEMBL23125001 | 0.80 | BCL9 (0.47) | KMT2AALDH1A1NPSR1HTTMEN1 | |
| SCHEMBL21540803 | 0.80 | MC4R (0.50) | ALDH1A1TAAR1 | |
| SCHEMBL23124999 | 0.80 | BCL9 (0.47) | KMT2AALDH1A1NPSR1HTTMEN1 | |
| SCHEMBL19992630 | 0.77 | HTR2C (0.53) | ALDH1A1TP53 | |
| SCHEMBL18019652 | 0.76 | ALDH1A1 (0.46) | PKMKMT2AALDH1A1TP53HTT | |
| SCHEMBL10030564 | 0.75 | SLC6A1 (0.57) | KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011131975-A1 | MICROSOMAL PROSTAGLANDIN E SYNTASE-1 INHIBITORS | Convergence Pharmaceuticals Limited (GB) | 2011-10-27 | — | — | WO | disclosed |
| WO-2011131975-A1 | MICROSOMAL PROSTAGLANDIN E SYNTASE-1 INHIBITORS | Convergence Pharmaceuticals Limited (GB) | 2011-10-27 | — | — | WO | disclosed |