Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2450367 | 0.83 | HTR2C (0.56) | HTR2CALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL4434645 | 0.83 | ALDH1A1 (0.70) | HTR2CALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL2444405 | 0.83 | ALDH1A1 (0.70) | HTR2CALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL29542019 | 0.81 | HTR2C (0.53) | HTR2CALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL21541003 | 0.80 | HTR2C (0.62) | HTR2CALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL2447403 | 0.80 | ALDH1A1 (0.73) | HTR2CALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL6861732 | 0.80 | HTR2C (0.62) | HTR2CALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL13745623 | 0.80 | HTR2C (0.53) | HTR2CALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL2579071 | 0.77 | PKM (0.58) | ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL694838 | 0.77 | HTR2C (0.52) | HTR2CALDH1A1USP2HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079741-A1 | PROCESS FOR PRODUCING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079741-A1 | PROCESS FOR PRODUCING HETEROCYCLIC COMPOUND | DHPS, QDPR, DPYD | HTR2C 199/4885ALDH1A1 229/4885USP2 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.