Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR1D | P28221 | 5/20 | 0.38 |
| ▸ | HTR1B | P28222 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 6/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25030239 | 0.82 | HTR1D (0.49) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL25030242 | 0.76 | HTR1D (0.42) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL25292886 | 0.76 | HTR6 (0.59) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL30565963 | 0.76 | HTR6 (0.59) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL30565961 | 0.76 | HTR6 (0.59) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL25791527 | 0.76 | HTR1A (0.54) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL25288264 | 0.75 | HTR6 (0.58) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL31211621 | 0.75 | HTR6 (0.58) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL25987681 | 0.74 | HTR1D (0.38) | HTR2AHTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL25791525 | 0.74 | HTR1A (0.42) | HTR2AHTR1DHTR1BHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122320-A1 | POLYPODAL SEROTONERGIC COMPOUNDS AND PRODRUGS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |