Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR1D | P28221 | 5/20 | 0.42 |
| ▸ | HTR1B | P28222 | 5/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25791525 | 0.82 | HTR1A (0.42) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL12559104 | 0.76 | HTR1A (0.67) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL25791529 | 0.76 | HTR2A (0.39) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL25103118 | 0.75 | HTR2A (0.67) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL25747597 | 0.71 | HTR1A (1.00) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL25748759 | 0.71 | HTR1A (0.74) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL25791365 | 0.69 | MTNR1A (0.47) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL30954332 | 0.69 | HTR2A (0.71) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL1163811 | 0.69 | HTR2A (0.71) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL27219351 | 0.69 | HTR6 (0.70) | HTR1AHTR2AHTR1DHTR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122320-A1 | POLYPODAL SEROTONERGIC COMPOUNDS AND PRODRUGS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |