SCHEMBL2579180

SCHEMBL2579180

COC(C(=O)Cl)C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9416774 0.85
SCHEMBL2289696 0.83 SMN1; SMN2 (0.40)
SCHEMBL27676887 0.81
SCHEMBL27310429 0.77 ALDH1A1 (0.40)
SCHEMBL11801385 0.73
SCHEMBL6575015 0.71
SCHEMBL918787 0.71
SCHEMBL660278 0.71
SCHEMBL8686530 0.71
SCHEMBL1427169 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160023998-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2016-01-28 US disclosed
US-9174924-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-11-03 US disclosed
US-20150259275-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2015-09-17 US disclosed
US-9045396-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-06-02 US disclosed
US-20140163253-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2014-06-12 US disclosed
US-8664429-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-20130310596-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2013-11-21 US disclosed
US-20120197037-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2012-08-02 US disclosed
US-8048980-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2011-11-01 US disclosed
US-20100168175-A1 ATPENINS BAYER CROPSCIENCE AG (DE) 2010-07-01 US disclosed
US-20100075500-A1 Metal polishing slurry and chemical mechanical polishing method FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20090082540-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-26 US disclosed
US-6121239-A SPECIFIED TRI- AND TETRA-PEPTIDES SERBIO (FR) 2000-09-19 US disclosed
EP-0812832-A1 Improved process for pyrimidinone compounds ROHM AND HAAS COMPANY (US) 1997-12-17 EP disclosed
EP-0317492-B1 Substituted dicarboxylic acids-bis(3,5-dicarbamoyl-2,4,6-triiodo-anilides), process for their preparation and X-ray contrast agents containing them SCHERING AG (DE) 1994-06-01 EP disclosed
EP-0308364-B1 Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them SCHERING AG (DE) 1993-11-10 EP disclosed
US-5225532-A SYMMETRICAL BIPEPTIDES CONTAINING A POLYALKYLENE GLYCOL RESIDUE, METHOD OF PREPARATION AND USE IN THE ASSAY OF PROTEASES SERBIO (FR) 1993-07-06 US disclosed
US-5073362-A DICARBOXYLIC ACID-BIS(3,5-DICARBAMOYL-2,4,6-TRIIODOANILIDES) AND X-RAY CONTRAST MEDIA CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1991-12-17 US disclosed
EP-0317492-A2 Substituted dicarboxylic acids-bis(3,5-dicarbamoyl-2,4,6-triiodo-anilides), process for their preparation and X-ray contrast agents containing them SCHERING AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed
EP-0308364-A2 Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them SCHERING AKTIENGESELLSCHAFT (DE) 1989-03-22 EP disclosed