⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11396493 | 0.75 | — | — | |
| SCHEMBL23415050 | 0.75 | — | — | |
| SCHEMBL2959573 | 0.75 | — | — | |
| SCHEMBL30096746 | 0.73 | — | — | |
| SCHEMBL2582323 | 0.73 | — | — | |
| SCHEMBL11801385 | 0.71 | — | — | |
| SCHEMBL28207988 | 0.71 | — | — | |
| SCHEMBL2579180 | 0.71 | — | — | |
| SCHEMBL4644783 | 0.71 | — | — | |
| SCHEMBL4629798 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872202-B2 | Pleuromutilin cinnamic acid ester compounds with activities against antibiotic-resistant infections | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2024-01-16 | — | — | US | disclosed |
| US-20230172889-A1 | PLEUROMUTILIN CINNAMIC ACID ESTER COMPOUNDS WITH ACTIVITIES AGAINST ANTIBIOTIC-RESISTANT INFECTIONS | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-06-08 | — | — | US | disclosed |
| CN-105636933-A | A method for preparing an intermediate of iopromide | DAE WOONG PHARMA | 2016-06-01 | — | — | CN | disclosed |
| US-8853230-B2 | Inhibitors of JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130137673-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| US-8367689-B2 | Inhibitors of JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20110005947-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| WO-2010129802-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20090221582-A1 | Piperazine Derivatives And Their Use In Therapy | VERNALIS (R&D) (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221582-A1 | Piperazine Derivatives And Their Use In Therapy | VERNALIS (R&D) (GB) | 2009-09-03 | — | — | US | disclosed |
| WO-2007057687-A1 | PIPERAZINE DERIVATIVES AND THEIR USE IN THERAPY | VERNALIS (R & D) LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
| CN-1720047-A | PgD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARM INC (US) | 2006-01-11 | — | — | CN | disclosed |
| CN-1177029-A | Process for trichromatic dyeing printing | CIBA GEIGY AG (CH) | 1998-03-25 | — | — | CN | disclosed |