Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 5/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22853821 | 1.00 | CES2 (0.35) | CES2BCHEACHEKDM4AKDM4C | |
| SCHEMBL26730085 | 0.83 | ALDH1A1 (0.48) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL24811376 | 0.83 | HTR2A (0.36) | — | |
| SCHEMBL260594 | 0.82 | THRA (0.36) | CES2KDM4AKDM4CMEN1FAAH | |
| SCHEMBL14558101 | 0.82 | TSHR (0.50) | KDM4AKDM4CMEN1KMT2AKDM5A | |
| SCHEMBL25793792 | 0.82 | PAOX (0.47) | ACHEKDM4AKDM4CKDM5AKDM7A | |
| SCHEMBL14558119 | 0.82 | TSHR (0.50) | KDM4AKDM4CMEN1KMT2AKDM5A | |
| SCHEMBL26997800 | 0.82 | PAOX (0.47) | ACHEKDM4AKDM4CKDM5AKDM7A | |
| SCHEMBL9973392 | 0.80 | CES2 (0.48) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL9973396 | 0.80 | CES2 (0.48) | CES2MEN1FAAHMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |