Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 8/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24615974 | 0.91 | HPGD (0.40) | HPGDTSHRMEN1KMT2ACNR1 | |
| SCHEMBL25793571 | 0.86 | TSHR (0.43) | TSHRMEN1KMT2ACASP2NAAA | |
| SCHEMBL29299619 | 0.85 | HPGD (0.42) | HPGDTSHRMEN1KMT2ACNR1 | |
| SCHEMBL29299575 | 0.84 | HPGD (0.41) | HPGDTSHRMEN1KMT2ACNR1 | |
| SCHEMBL25791358 | 0.84 | TP53 (0.44) | HPGDTSHRMEN1KMT2ACNR1 | |
| SCHEMBL26482295 | 0.84 | MEN1 (0.41) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL25791257 | 0.83 | TP53 (0.41) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL23320104 | 0.83 | TSHR (0.46) | HPGDTSHRCNR1LMNAPKM | |
| SCHEMBL24811342 | 0.83 | ALDH1A1 (0.44) | HPGDTSHRMEN1KMT2ACNR1 | |
| SCHEMBL24811366 | 0.83 | TSHR (0.38) | TSHRMEN1KMT2AALDH1A1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |