Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25793560 | 0.88 | KDM4E (0.40) | TSHRCASP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25793571 | 0.86 | TSHR (0.43) | TSHRCASP2MEN1KMT2ANAAA | |
| SCHEMBL25791250 | 0.84 | TSHR (0.39) | TSHRCASP2ADRB2ADRB1MEN1 | |
| SCHEMBL25792485 | 0.83 | CASP2 (0.41) | TSHRCASP2ADRB2ADRB1MEN1 | |
| SCHEMBL25793735 | 0.83 | HPGD (0.40) | TSHRCASP2MEN1KMT2ANAAA | |
| SCHEMBL25793537 | 0.82 | TSHR (0.51) | TSHRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL24811017 | 0.82 | TSHR (0.51) | TSHRADRB2ADRB1MEN1KMT2A | |
| SCHEMBL29300199 | 0.82 | CASP2 (0.53) | CASP2NAAAFAAH | |
| SCHEMBL25836541 | 0.82 | MEN1 (0.42) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29300154 | 0.81 | CASP2 (0.51) | CASP2NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |