Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | SAT1 | P21673 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24813893 | 0.92 | TSHR (0.40) | TSHRCASP2SAT1MEN1KMT2A | |
| SCHEMBL20469919 | 0.87 | CASP2 (0.42) | TSHRCASP2MEN1KMT2ANAAA | |
| SCHEMBL25791257 | 0.87 | TP53 (0.41) | TSHRCASP2SAT1MEN1KMT2A | |
| SCHEMBL24982536 | 0.87 | MEN1 (0.40) | TSHRCASP2MEN1KMT2ANAAA | |
| SCHEMBL24811366 | 0.86 | TSHR (0.38) | TSHRCASP2MEN1KMT2ACYP2C19 | |
| SCHEMBL25793735 | 0.86 | HPGD (0.40) | TSHRCASP2MEN1KMT2ANAAA | |
| SCHEMBL25793560 | 0.86 | KDM4E (0.40) | TSHRCASP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15679068 | 0.81 | LMNA (0.36) | SAT1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12312753 | 0.81 | SMN1; SMN2 (0.55) | TSHRSMN1; SMN2POLBEPHX2 | |
| SCHEMBL26482295 | 0.81 | MEN1 (0.41) | MEN1KMT2ACYP2C19SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |