⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23806409 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL25726062 | 0.78 | — | — | |
| SCHEMBL25792823 | 0.78 | CA12 (0.38) | — | |
| SCHEMBL25792818 | 0.78 | MEN1 (0.32) | — | |
| SCHEMBL1106961 | 0.76 | — | — | |
| SCHEMBL24813890 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL25792829 | 0.75 | CA2 (0.32) | — | |
| SCHEMBL25792841 | 0.73 | CYP1A2 (0.32) | — | |
| Methane SCHEMBL28228146 | 0.72 | CA2 (0.42) | — | |
| SCHEMBL15241254 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |