Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE8B | O95263 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25794224 | 0.90 | USP28 (1.00) | USP28MEN1KMT2AKDM1AKDM4E | |
| SCHEMBL25809849 | 0.85 | USP28 (0.69) | USP28MEN1KMT2AKDM1AKDM4E | |
| SCHEMBL25794259 | 0.85 | USP28 (0.68) | USP28MEN1KMT2AKDM1AKDM4E | |
| SCHEMBL25809850 | 0.82 | USP28 (0.69) | USP28MEN1KMT2AKDM1AALDH1A1 | |
| SCHEMBL25794196 | 0.82 | USP28 (0.69) | USP28MEN1KMT2AKDM1AKDM4E | |
| SCHEMBL25827780 | 0.81 | USP28 (0.85) | USP28MEN1KMT2AKDM1A | |
| SCHEMBL25794181 | 0.81 | USP28 (0.84) | USP28MEN1KMT2AKDM1A | |
| SCHEMBL25795471 | 0.81 | USP28 (0.84) | USP28MEN1KMT2AKDM1A | |
| SCHEMBL25795474 | 0.80 | USP28 (0.68) | USP28MEN1KMT2AKDM1AKDM4E | |
| SCHEMBL25795472 | 0.80 | USP28 (0.83) | USP28MEN1KMT2AKDM1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |