Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.68 |
| ▸ | KDM1A | O60341 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25794195 | 0.85 | USP28 (0.81) | USP28KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL25794224 | 0.81 | USP28 (1.00) | USP28KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL25809849 | 0.77 | USP28 (0.69) | USP28KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL2065766 | 0.75 | P2RY12 (0.53) | KDM1AALDH1A1HPGDPOLBCYP2C9 | |
| SCHEMBL10074050 | 0.75 | P2RY12 (0.53) | KDM1AALDH1A1HPGDPOLBCYP2C9 | |
| SCHEMBL5002843 | 0.75 | P2RY12 (0.53) | KDM1AALDH1A1HPGDPOLBCYP2C9 | |
| SCHEMBL25795474 | 0.74 | USP28 (0.68) | USP28KDM1AMEN1KMT2AKDM4E | |
| SCHEMBL25795472 | 0.74 | USP28 (0.83) | USP28KDM1AMEN1KMT2AKDM4E | |
| SCHEMBL2065688 | 0.74 | P2RY12 (0.62) | ALDH1A1POLBCYP2C9NPSR1CYP1A2 | |
| SCHEMBL25794196 | 0.74 | USP28 (0.69) | USP28KDM1AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |