Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.69 |
| ▸ | KDM1A | O60341 | 11/20 | 0.54 |
| ▸ | PDE8B | O95263 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809918 | 0.90 | KDM1A (0.66) | USP28KDM1AMEN1KMT2A | |
| SCHEMBL25794195 | 0.85 | USP28 (0.81) | USP28KDM1APDE8BMEN1KMT2A | |
| SCHEMBL25808561 | 0.82 | KDM1A (0.55) | USP28KDM1APDE8BMEN1KMT2A | |
| SCHEMBL25794224 | 0.82 | USP28 (1.00) | USP28KDM1AMEN1KMT2AKDM4E | |
| SCHEMBL25794259 | 0.77 | USP28 (0.68) | USP28KDM1AMEN1KMT2AKDM4E | |
| SCHEMBL25794181 | 0.73 | USP28 (0.84) | USP28KDM1AMEN1KMT2A | |
| SCHEMBL25827780 | 0.73 | USP28 (0.85) | USP28KDM1AMEN1KMT2A | |
| SCHEMBL25795471 | 0.72 | USP28 (0.84) | USP28KDM1AMEN1KMT2A | |
| SCHEMBL4845513 | 0.72 | XDH (0.43) | USP28KDM1AMEN1KMT2ACYP1A2 | |
| SCHEMBL25795474 | 0.71 | USP28 (0.68) | USP28KDM1AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |