Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25794232 | 0.74 | USP28 (0.50) | ESR1ESR2LMNAHRH4 | |
| Hydrochloric Acid SCHEMBL7093198 | 0.63 | HRH3 (0.50) | ESR1ESR2LMNACETPHRH3 | |
| SCHEMBL4316313 | 0.59 | ESR1 (1.00) | ESR1ESR2CETP | |
| SCHEMBL4025742 | 0.57 | HDAC3 (0.54) | LMNA | |
| SCHEMBL9083039 | 0.55 | KDM4E (0.51) | LMNA | |
| SCHEMBL604139 | 0.55 | HRH4 (0.56) | CETPHRH3HRH4SOS1KCNH2 | |
| SCHEMBL7433560 | 0.54 | ADRB1 (0.49) | LMNACETPHTR3EHTR3BADRB1 | |
| Propylamine SCHEMBL8390972 | 0.54 | ADRB1 (0.73) | LMNACETPCYP1A2CYP2D6HTR3E | |
| SCHEMBL588594 | 0.54 | ADRB1 (0.79) | CETPCYP1A2CYP2D6HTR3EHTR3B | |
| SCHEMBL17822440 | 0.53 | HRH4 (0.56) | HRH3HRH4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |