Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 9/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25795475 | 0.78 | KDM1A (0.56) | USP28CNR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25794215 | 0.74 | ESR1 (0.42) | HRH4ESR1ESR2LMNA | |
| SCHEMBL25809849 | 0.67 | USP28 (0.69) | USP28CNR2HRH4PDE8BALDH1A1 | |
| SCHEMBL25794224 | 0.67 | USP28 (1.00) | USP28ALDH1A1LMNAKDM1A | |
| SCHEMBL31550410 | 0.65 | HRH4 (0.52) | CNR2HRH4PDE8BALDH1A1LMNA | |
| SCHEMBL25794225 | 0.65 | USP28 (0.78) | USP28PDE8BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25794195 | 0.64 | USP28 (0.81) | USP28PDE8BALDH1A1LMNAKDM1A | |
| SCHEMBL25808561 | 0.62 | KDM1A (0.55) | USP28HRH4PDE8BALDH1A1LMNA | |
| SCHEMBL25794118 | 0.62 | USP28 (0.77) | USP28CNR2PDE8BALDH1A1LMNA | |
| SCHEMBL25794260 | 0.62 | USP28 (0.74) | USP28PDE8BALDH1A1LMNAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |