Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY8 | P40145 | 1/20 | 0.37 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25795137 | 0.91 | NOTUM (0.37) | ADCY8ADCY1NOTUMPTPN5 | |
| SCHEMBL28752822 | 0.84 | PRKAB2 (0.34) | OPRK1MYCWDR5 | |
| SCHEMBL10104276 | 0.82 | ADCY8 (0.42) | ADCY8ADCY1NOTUMPTPN5 | |
| SCHEMBL16729426 | 0.79 | NOTUM (0.46) | ADCY8ADCY1NOTUMPTPN5 | |
| SCHEMBL25795139 | 0.75 | HTR1A (0.39) | NOTUM | |
| SCHEMBL10553055 | 0.74 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL18781907 | 0.74 | ADCY8 (0.37) | ADCY8ADCY1NOTUMPTPN5 | |
| SCHEMBL18051411 | 0.73 | HTR2C (0.50) | PTPN5 | |
| SCHEMBL7786250 | 0.73 | HTR1A (0.38) | ADCY8ADCY1NOTUM | |
| SCHEMBL15787250 | 0.72 | NOTUM (0.41) | ADCY8ADCY1NOTUMPTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109912-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2023-06-22 | — | — | WO | disclosed |