SCHEMBL257958

SCHEMBL257958

COB(C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.46
ORAI1 Q96D31 2/20 0.43
ORAI2 Q96SN7 2/20 0.43
ORAI3 Q9BRQ5 2/20 0.43
TRPV6 Q9H1D0 2/20 0.43
CA7 P43166 3/20 0.39
CA14 Q9ULX7 3/20 0.39
ENPP2 Q13822 3/20 0.39
PCSK9 Q8NBP7 2/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
LTA4H P09960 2/20 0.39
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA12 O43570 2/20 0.35
CA9 Q16790 2/20 0.35
TRPA1 O75762 1/20 0.34
TSHR P16473 4/20 0.33
MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17233749 0.80 TRPV6 (0.52) CA4ORAI1ORAI2ORAI3TRPV6
SCHEMBL7796734 0.74 ORAI1 (0.60) CA4ORAI1ORAI2ORAI3TRPV6
SCHEMBL309077 0.74 CA4 (0.48) CA4ORAI1ORAI2ORAI3TRPV6
Ammonia Solution, Strong SCHEMBL28822149 0.72 CA4 (0.46) CA4ORAI1ORAI2ORAI3TRPV6
Water SCHEMBL27700277 0.72 CA4 (0.46) CA4ORAI1ORAI2ORAI3TRPV6
SCHEMBL14392454 0.72 ORAI1 (0.39) CA4ORAI1ORAI2ORAI3TRPV6
SCHEMBL28994680 0.72 TSHR (0.39) CA4ORAI1ORAI2ORAI3TRPV6
Water SCHEMBL27720259 0.70 TSHR (0.38) CA4ORAI1ORAI2ORAI3TRPV6
SCHEMBL14493121 0.70 TRPV6 (0.48) CA4ORAI1ORAI2ORAI3TRPV6
SCHEMBL691860 0.70 ENPP2 (0.50) CA4ORAI1ORAI2ORAI3TRPV6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063604-B Bimodal polyethylene resin for pipe material product, preparation method thereof and pipe material product 中国石油化工股份有限公司 2024-11-19 CN disclosed
US-12012639-B2 Processes for isolation and recovery of C5 sugars UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2024-06-18 US disclosed
CN-116063604-A Bimodal polyethylene resin for pipe material product, preparation method thereof and pipe material product 中国石油化工股份有限公司 2023-05-05 CN disclosed
US-20220052275-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-02-17 US disclosed
US-20210071273-A1 PROCESSES FOR ISOLATION AND RECOVERY OF C5 SUGARS UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. 2021-03-11 US disclosed
EP-3710603-A1 PROCESSES FOR ISOLATION AND RECOVERY OF C5 SUGARS University Of Louisville Research Foundation, Inc. (US) 2020-09-23 EP disclosed
WO-2019118476-A1 PROCESSES FOR ISOLATION AND RECOVERY OF C5 SUGARS UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2019-06-20 WO disclosed
US-10242874-B2 Diffusing agent composition and method of manufacturing semiconductor substrate TOKYO OHKA KOGYO CO., LTD. (JP) 2019-03-26 US disclosed
US-20180374704-A1 DIFFUSING AGENT COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR SUBSTRATE TOKYO OHKA KOGYO CO., LTD. (JP) 2018-12-27 US disclosed
US-9056822-B2 Method for producing polycyclic aromatic compound substituted by aryl group NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2015-06-16 US disclosed
US-20140206908-A1 METHOD FOR PRODUCING POLYCYCLIC AROMATIC COMPOUND SUBSTITUTED BY ARYL GROUP NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-07-24 US disclosed
US-8450442-B2 Borosiloxane composition, borosiloxane adhesive, coated and laminated substrates DOW CORNING CORPORATION (US) 2013-05-28 US disclosed
EP-2399585-A1 Boronic acids and esters as inhibitors of fatty acid amide hydrolase Infinity Pharmaceuticals, Inc. (US) 2011-12-28 EP disclosed
US-20110021736-A1 Polyborosiloxane and Method of Preparing Same DOW CORNING CORPORATION 2011-01-27 US disclosed
US-20100316876-A1 Borosiloxane Composition, Borosiloxane Adhesive, Coated and Laminated Substrates DOW CORNING CORPORATION 2010-12-16 US disclosed
EP-2254933-A1 POLYBOROSILOXANE AND METHOD OF PREPARING SAME Dow Corning Corporation (US) 2010-12-01 EP disclosed
EP-2254934-A1 BOROSILOXANE COMPOSITION, BOROSILOXANE ADHESIVE, COATED AND LAMINATED SUBSTRATES Dow Corning Corporation (US) 2010-12-01 EP disclosed
WO-2009111193-A1 BOROSILOXANE COMPOSITION, BOROSILOXANE ADHESIVE, COATED AND LAMINATED SUBSTRATES DOW CORNING CORPORATION (US) 2009-09-11 WO disclosed
WO-2009111191-A1 POLYBOROSILOXANE AND METHOD OF PREPARING SAME DOW CORNING CORPORATION (US) 2009-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052275-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC CA4 4574/4885ORAI1 880/4885ORAI2 224/4885
US-20140206908-A1 METHOD FOR PRODUCING POLYCYCLIC AROMATIC COMPOUND SUBSTITUTED BY ARYL GROUP PAH, DBH, AHR CA4 35/4885ORAI1 2897/4885ORAI2 2215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.