SCHEMBL7796734

SCHEMBL7796734

COB(c1ccccc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 2/20 0.60
ORAI2 Q96SN7 2/20 0.60
ORAI3 Q9BRQ5 2/20 0.60
TRPV6 Q9H1D0 2/20 0.60
CA4 P22748 3/20 0.48
TSHR P16473 3/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
ALOX12 P18054 2/20 0.44
MAPK1 P28482 2/20 0.44
MEN1 O00255 1/20 0.44
TRPM2 O94759 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
THRB P10828 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA7 P43166 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16151497 0.88 ORAI1 (0.48) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL16300534 0.85 MGLL (0.50) ORAI1ORAI2ORAI3TRPV6ALDH1A1
SCHEMBL309077 0.77 CA4 (0.48) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL435243 0.75 TRPV6 (1.00) ORAI1ORAI2ORAI3TRPV6CA4
Ammonia Solution, Strong SCHEMBL28822149 0.74 CA4 (0.46) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL257958 0.74 CA4 (0.46) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL14493121 0.72 TRPV6 (0.48) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL4174839 0.72 ORAI1 (0.46) ORAI1ORAI2ORAI3TRPV6ALDH1A1
SCHEMBL4175868 0.72 ENPP2 (0.46) ORAI1ORAI2ORAI3TRPV6MEN1
SCHEMBL28993943 0.72 CA4 (0.43) ORAI1ORAI2ORAI3TRPV6CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063604-B Bimodal polyethylene resin for pipe material product, preparation method thereof and pipe material product 中国石油化工股份有限公司 2024-11-19 CN disclosed
CN-116063604-A Bimodal polyethylene resin for pipe material product, preparation method thereof and pipe material product 中国石油化工股份有限公司 2023-05-05 CN disclosed
CN-112020520-B Method for producing allyl monomer copolymer having polar group 国立大学法人东京大学 2023-03-10 CN disclosed
US-20090082561-A1 Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids THE PENNSYLVANIA STATE RESEARCH FOUNDATION 2009-03-26 US disclosed
US-7405304-B2 Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids THE PENN STATE RESEARCH FOUNDATION (US) 2008-07-29 US disclosed
EP-0808849-B1 Process for the production of ethylenic polymers SHOWA DENKO KK (JP) 2001-12-19 EP disclosed
US-6011127-A CATALYST COMPRISING A CHROMIUM COMPOUND, AN ALUMOXANE AND AN ORGANOMETALLIC ALKOXIDE AND/OR ORGANOMETALLIC SILOXIDE AND A CARRIER SUPPORTING THEREON THESE COMPOUNDS. SHOWA DENKO K.K. (JP) 2000-01-04 US disclosed
EP-0574258-B1 Process for producing alpha-olefin polymers MITSUBISHI CHEM CORP (JP) 1998-01-14 EP disclosed
EP-0808849-A1 Process for the production of ethylenic polymers SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-11-26 EP disclosed
EP-0519496-B1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same TONEN CORP (JP) 1996-05-22 EP disclosed
EP-0404503-B1 Boron-containing, silicon nitride-based ceramic shaped body production process TONEN CORP (JP) 1996-03-06 EP disclosed
EP-0389084-B1 Process for producing a polyborosilazane TONEN CORP (JP) 1995-09-20 EP disclosed
US-5292830-A Silane, silazane, boron block crosslinked copolymers TONEN CORPORATION (JP) 1994-03-08 US disclosed
EP-0574258-A2 Process for producing alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1993-12-15 EP disclosed
EP-0519496-A1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same Tonen Corporation (JP) 1992-12-23 EP disclosed
US-5030744-A Polyborosilazane and process for producing same TONEN CORPORATION (JP) 1991-07-09 US disclosed
EP-0404503-A1 Boron-containing, silicon nitride-based ceramic shaped body production process Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0389084-A2 Process for producing a polyborosilazane Tonen Corporation (JP) 1990-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090082561-A1 Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids BCL6B, BLVRB, SSB ORAI1 1065/4885ORAI2 874/4885ORAI3 747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.