Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20242265 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNASLC6A5NPC1 | |
| SCHEMBL6318350 | 0.85 | ADRB1 (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL17631929 | 0.83 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNASLC6A5HTT | |
| SCHEMBL2062084 | 0.83 | SLC6A5 (0.64) | ALDH1A1SMN1; SMN2LMNASLC6A5HTT | |
| SCHEMBL29788533 | 0.83 | SLC6A5 (0.64) | ALDH1A1SMN1; SMN2LMNASLC6A5HTT | |
| SCHEMBL4362315 | 0.82 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNASLC6A5MAPT | |
| SCHEMBL29791350 | 0.82 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2LMNASLC6A5NPC1 | |
| SCHEMBL25796967 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNASLC6A5NPC1 | |
| SCHEMBL25797097 | 0.82 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNASLC6A5NPC1 | |
| SCHEMBL12528187 | 0.82 | SLC6A5 (0.63) | ALDH1A1SMN1; SMN2LMNASLC6A5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203042-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203042-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | SYK, BTK, LCK | ALDH1A1 2839/4885SMN1; SMN2 4680/4885LMNA 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.