Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339523 | 0.88 | IDO1 (0.58) | IDO1GPR84BRD4ALDH1A1ATM | |
| SCHEMBL12260702 | 0.82 | IDO1 (0.49) | IDO1GPR84BRD4ALDH1A1ATM | |
| SCHEMBL29890737 | 0.79 | IDO1 (0.62) | IDO1GPR84ALDH1A1KMT2A | |
| SCHEMBL20433788 | 0.79 | IDO1 (0.62) | IDO1GPR84ALDH1A1KMT2A | |
| SCHEMBL10340150 | 0.79 | IDO1 (0.62) | IDO1GPR84ALDH1A1KMT2A | |
| SCHEMBL14503416 | 0.77 | IDO1 (0.44) | IDO1GPR84PRCPALDH1A1DHODH | |
| SCHEMBL17526328 | 0.77 | IDO1 (0.56) | IDO1GPR84ALDH1A1KMT2A | |
| SCHEMBL20433856 | 0.76 | GPR84 (0.59) | IDO1GPR84ALDH1A1 | |
| SCHEMBL19529546 | 0.76 | GPR84 (0.59) | IDO1GPR84ALDH1A1 | |
| SCHEMBL5382522 | 0.76 | IDO1 (0.42) | IDO1GPR84PRCPALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| EP-2073816-B1 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS INC (US) | 2011-09-14 | — | — | EP | disclosed |
| WO-2008063300-A2 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-29 | — | — | WO | disclosed |