Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20463424 | 0.83 | MTNR1A (0.72) | GAALMNAKMT2AHPGDHSD17B10 | |
| SCHEMBL25797688 | 0.80 | LMNA (0.51) | LMNAMEN1PKMKMT2AHPGD | |
| SCHEMBL10568006 | 0.76 | CA12 (0.55) | GAAJAK2LMNAMAPTMEN1 | |
| SCHEMBL9152183 | 0.75 | GAA (0.72) | GAAJAK2LMNAMAPTHPGD | |
| SCHEMBL2234017 | 0.75 | GAA (0.72) | GAAJAK2LMNAMAPTHPGD | |
| SCHEMBL2637278 | 0.74 | GAA (0.95) | GAAJAK2LMNAMAPTHPGD | |
| SCHEMBL32679977 | 0.74 | GAA (0.64) | GAAJAK2LMNAMAPTALDH1A1 | |
| SCHEMBL13715506 | 0.74 | GAA (0.64) | GAAJAK2LMNAMAPTALDH1A1 | |
| Methane SCHEMBL7356487 | 0.73 | GAA (0.69) | GAAJAK2LMNAMAPTHPGD | |
| SCHEMBL5621969 | 0.72 | GAA (0.82) | GAAJAK2LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125751-A1 | DIA-BASED QUANTITATIVE CHEMICAL PROTEOMICS TARGET SCREENING METHOD | 北京大学 | 2023-07-06 | — | — | WO | disclosed |