Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17623911 | 0.84 | SLC6A2 (0.45) | MRGPRX1F10ACHESLC6A2SLC6A4 | |
| SCHEMBL7938427 | 0.83 | MAPT (0.46) | ACHESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL10269468 | 0.83 | FFAR1 (0.43) | MRGPRX1F10ACHESLC6A2SLC6A4 | |
| SCHEMBL22185410 | 0.82 | LTA4H (0.52) | — | |
| SCHEMBL3179032 | 0.81 | SLC6A2 (0.48) | ACHESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL6293197 | 0.81 | ALDH1A1 (0.50) | ACHESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL6289878 | 0.81 | ALDH1A1 (0.50) | ACHESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL6293224 | 0.81 | ALDH1A1 (0.50) | ACHESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL6289927 | 0.81 | ALDH1A1 (0.50) | ACHESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL6290410 | 0.81 | ALDH1A1 (0.50) | ACHESLC6A2SLC6A4SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404607-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |