SCHEMBL3378627

SCHEMBL3378627

C=C[Si](C)(C)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
CYP2A6 P11509 1/20 0.38
ALDH1A1 P00352 2/20 0.36
PYCR1 P32322 1/20 0.34
TGM2 P21980 2/20 0.32
F13A1 P00488 1/20 0.32
LMNA P02545 1/20 0.32
TGM1 P22735 1/20 0.32
TGM3 Q08188 1/20 0.32
MMP9 P14780 2/20 0.32
ALOX15 P16050 2/20 0.31
MAPK1 P28482 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12032183 0.94 NR1H2 (0.46) NR1H2NR1H3CYP2A6ALDH1A1PYCR1
SCHEMBL678612 0.87 NR1H2 (0.59) NR1H2NR1H3
SCHEMBL2579803 0.80 NR1H2 (0.53) NR1H2NR1H3
SCHEMBL3378809 0.78 NR1H2 (0.52) NR1H2NR1H3CYP2A6ALDH1A1TGM2
SCHEMBL10324259 0.76 NR1H2 (0.50) NR1H2NR1H3ALDH1A1LMNAALOX15
SCHEMBL31231940 0.76 NR1H2 (0.55) NR1H2NR1H3TGM2IDO1
SCHEMBL10540578 0.76 NR1H2 (0.50) NR1H2NR1H3CYP2A6LMNAMMP9
SCHEMBL2558126 0.76 NR1H2 (0.55) NR1H2NR1H3ALDH1A1LMNAALOX15
SCHEMBL7712417 0.76 ALDH1A1 (0.52) NR1H2NR1H3ALDH1A1
SCHEMBL453982 0.75 NR1H2 (0.48) NR1H2NR1H3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504742-B1 SILICONE-SOLUBLE ACYLPHOSPHINE OXIDE PHOTOINITIATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2026-05-20 EP disclosed
US-20250215160-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-03 US disclosed
US-20250206889-A1 SILICONE-SOLUBLE ACYLPHOSPHINE OXIDE PHOTOINITIATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-26 US disclosed
WO-2025064221-A1 PHOTOCURABLE ORGANOPOLYSILOXANE RESIN DOW GLOBAL TECHNOLOGIES LLC (US) 2025-03-27 WO disclosed
WO-2025064220-A1 PHOTOCURABLE ORGANOPOLYSILOXANE RESIN DOW GLOBAL TECHNOLOGIES LLC (US) 2025-03-27 WO disclosed
EP-4504741-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATOR Dow Global Technologies LLC (US) 2025-02-12 EP disclosed
EP-4504742-A1 SILICONE-SOLUBLE ACYLPHOSPHINE OXIDE PHOTOINITIATOR Dow Global Technologies LLC (US) 2025-02-12 EP disclosed
CN-118946573-A Acyl phosphine oxide photoinitiator 陶氏环球技术有限责任公司 2024-11-12 CN disclosed
WO-2023196158-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-12 WO disclosed
WO-2023196157-A1 SILICONE-SOLUBLE ACYLPHOSPHINE OXIDE PHOTOINITIATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-12 WO disclosed
WO-2020116367-A1 POLYBUTADIENE AND METHOD FOR PRODUCING SAME 宇部興産株式会社 2020-06-11 WO disclosed
EP-1452549-B1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO LTD (JP) 2010-11-17 EP disclosed
US-7629419-B2 Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO., LTD. (JP) 2009-12-08 US disclosed
CN-1289538-C Method for producing modified polymer compound, apparatus for producing modified polymer compound, and modified polymer compound SEKISUI CHEMICAL CO LTD (JP) 2006-12-13 CN disclosed
US-20050053792-A1 High purity; using supercritical fluid; high temperature; high pressure; polyolefins; interface film for glass; ceramic binder SEKISUI CHEMICAL CO., LTD. (JP) 2005-03-10 US disclosed
CN-1571801-A Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO LTD (JP) 2005-01-26 CN disclosed
EP-1452549-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2004-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206889-A1 SILICONE-SOLUBLE ACYLPHOSPHINE OXIDE PHOTOINITIATOR MSR1, PIGS, F12 NR1H2 139/4885NR1H3 84/4885CYP2A6 2611/4885
US-20250215160-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATOR ARSA, H1-3, MPST NR1H2 788/4885NR1H3 455/4885CYP2A6 1628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.