Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 12/20 | 0.60 |
| ▸ | IL1B | P01584 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25798433 | 0.89 | NLRP3 (0.60) | NLRP3IL1BKCNH2 | |
| SCHEMBL25799048 | 0.88 | NLRP3 (0.66) | NLRP3IL1BKCNH2CAMK2DADORA2A | |
| SCHEMBL25797696 | 0.87 | IL1B (0.60) | NLRP3IL1BKCNH2 | |
| SCHEMBL25798457 | 0.86 | IL1B (0.74) | NLRP3IL1B | |
| SCHEMBL31367796 | 0.83 | NLRP3 (0.52) | NLRP3IL1BKCNH2CAMK2DADORA2A | |
| SCHEMBL25519368 | 0.83 | NLRP3 (0.57) | NLRP3IL1BKCNH2CAMK2DADORA2A | |
| SCHEMBL30517832 | 0.83 | NLRP3 (0.57) | NLRP3IL1BKCNH2CAMK2DADORA2A | |
| SCHEMBL25798660 | 0.83 | IL1B (0.56) | NLRP3IL1BKCNH2 | |
| SCHEMBL30665787 | 0.82 | NLRP3 (0.55) | NLRP3IL1BKCNH2CAMK2D | |
| SCHEMBL25798598 | 0.82 | NLRP3 (0.42) | NLRP3IL1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129987-A1 | PYRIDAZINE DERIVATIVES AS MODULATORS OF NLRP3 INFLAMMASOME AND RELATED METHODS | Neumora Therapeutics, Inc. (US) | 2023-07-06 | — | — | WO | disclosed |