SCHEMBL25800414

SCHEMBL25800414

CNC(=O)c1ccc(-c2ccc(C(=O)Nc3ccc(-c4ccc(C)cc4C(F)(F)F)c(C(F)(F)F)c3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.59
▸ MEN1 O00255 3/20 0.59
▸ KMT2A Q03164 3/20 0.59
▸ NPC1 O15118 3/20 0.59
▸ RAB9A P51151 3/20 0.59
▸ NPSR1 Q6W5P4 2/20 0.59
▸ HTT P42858 2/20 0.59
▸ TRPV1 Q8NER1 2/20 0.50
▸ XBP1 P17861 1/20 0.49
▸ LMNA P02545 2/20 0.46
▸ MCHR1 Q99705 2/20 0.45
▸ KDR P35968 2/20 0.44
▸ KCNK3 O14649 1/20 0.44
▸ KCNK9 Q9NPC2 1/20 0.44
▸ PDK2 Q15119 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ CA12 O43570 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ CA7 P43166 1/20 0.43
▸ CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25800418 0.96 RAB9A (0.63) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL15445486 0.94 MAPT (0.56) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL15445485 0.91 MEN1 (0.59) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL18844920 0.89 MAPT (0.58) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL16255702 0.86 AKR1C3 (0.51) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL23802604 0.85 NPC1 (0.61) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL21018547 0.84 MAPT (0.60) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL15445483 0.83 KCNK3 (0.52) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL25844611 0.83 NPC1 (0.68) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL12994272 0.81 S1PR1 (0.47) MAPTMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037473-B2 Polyamide-imide film and method for producing same SK MICROWORKS CO., LTD. (KR) 2024-07-16 — — US disclosed
US-11702519-B2 Polyamide-imide film and method for preparing same SKC microworks CO., LTD. (KR) 2023-07-18 — — US disclosed
US-11702519-B2 Polyamide-imide film and method for preparing same SKC microworks CO., LTD. (KR) 2023-07-18 — — US disclosed
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