SCHEMBL25801463

SCHEMBL25801463

CN(C)C(=O)[C@H](CC(=O)OC(C)(C)C)N(C)C(=O)[C@H](C1CCCC1)N(C)OC(=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
LMNA P02545 1/20 0.35
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
USP30 Q70CQ3 3/20 0.32
HTR2C P28335 2/20 0.31
SLC6A4 P31645 2/20 0.31
CASR P41180 1/20 0.31
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25801540 0.81 LMNA (0.34) CYP1A2CYP2D6LMNASCN1ASCN2A
SCHEMBL24734869 0.81 ABCB1 (0.40) CYP2C19L3MBTL1HTR2CSLC6A4
SCHEMBL25801485 0.80 HDAC3 (0.31)
SCHEMBL25801634 0.75
SCHEMBL25801462 0.74 LMNA (0.45) CYP1A2CYP2D6LMNASCN1ASCN2A
SCHEMBL24733718 0.73 CTSS (0.40) ALDH1A1L3MBTL1KMT2AHTR2CSLC6A4
SCHEMBL24733706 0.73
SCHEMBL24733659 0.73
SCHEMBL25801572 0.73
SCHEMBL30051418 0.72 EPHX1 (0.32) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023127869-A1 METHOD FOR PRODUCING N-ALKYL AMINO ACID AND PEPTIDE INCLUDING N-ALKYL AMINO ACID 中外製薬株式会社 2023-07-06 WO disclosed