SCHEMBL4941110

SCHEMBL4941110

O=C(O)c1ccc(C(=O)OCc2ccccc2)c(C(=O)OCc2ccccc2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
TDP1 Q9NUW8 4/20 0.59
KMT2A Q03164 3/20 0.59
SLC6A2 P23975 1/20 0.59
SLC6A3 Q01959 1/20 0.59
LMNA P02545 3/20 0.58
CYP3A4 P08684 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
MAPT P10636 2/20 0.51
HPGD P15428 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
NR4A2 P43354 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5834481 0.95 ALDH1A1 (0.62) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL5834914 0.95 ALDH1A1 (0.71) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL4938474 0.95 ALDH1A1 (0.71) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL2580214 0.92 TDP1 (0.66) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL16016782 0.90 ALDH1A1 (0.63) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL12114076 0.88 ALDH1A1 (0.69) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL17158210 0.88 ALDH1A1 (0.59) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL20830629 0.86 ALDH1A1 (0.58) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL1316640 0.85 ALDH1A1 (0.56) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL2588443 0.84 ALDH1A1 (0.72) ALDH1A1TDP1KMT2ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080004387-A1 Alkyl benzyl esters of polycarboxylic acids LANXESS DEUTSCHLAND GMBH (DE) 2008-01-03 US disclosed