SCHEMBL25802461

SCHEMBL25802461

CC(COc1ccc(I)cc1I)NS(=O)(=O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 10/20 0.33
XDH P47989 1/20 0.32
CA2 P00918 2/20 0.32
SLC2A1 P11166 1/20 0.31
CNR1 P21554 1/20 0.31
CA1 P00915 1/20 0.31
GRIA4 P48058 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662013 0.75 NR3C1 (0.36) NR3C1CNR1GRIA4
SCHEMBL25802453 0.75 IDO1 (0.42) CA2CNR1CA1
SCHEMBL31661922 0.71 GRIA4 (0.34) NR3C1CNR1GRIA4
SCHEMBL23843715 0.71 ALDH1A1 (0.34) CNR1
Hydrochloric Acid SCHEMBL31661889 0.69 HTR2A (0.35) CA2CNR1CA1GRIA4
Hydrochloric Acid SCHEMBL31602270 0.69 SLC2A1 (0.46) NR3C1SLC2A1
SCHEMBL32661206 0.68 CNR1 (0.39) NR3C1CNR1GRIA4
SCHEMBL5917971 0.67 ACHE (0.37)
SCHEMBL28840400 0.67 ATM (0.39) CA2CA1
SCHEMBL28840409 0.67 ATM (0.39) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023119910-A1 RADIATION-SENSITIVE COMPOSITION, RESIST PATTERN FORMATION METHOD, ACID GENERATOR, AND COMPOUND JSR株式会社 2023-06-29 WO disclosed