Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 1/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340400 | 0.92 | CYP1A2 (0.50) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL23340399 | 0.81 | CYP1A2 (0.48) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL22692943 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL23046634 | 0.80 | CYP1A2 (0.39) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL22692958 | 0.78 | CYP1A2 (0.38) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL23046629 | 0.76 | ALDH1A1 (0.40) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL167302 | 0.73 | MAPT (0.51) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL23046636 | 0.72 | GSK3B (0.43) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL23872752 | 0.71 | CYP1A2 (0.49) | CYP1A2CYP3A4HTR1ASCN1ASCN2A | |
| SCHEMBL2728475 | 0.70 | MAPT (0.49) | CYP1A2CYP3A4HTR1ASCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696912-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696912-B2 | Charged ion channel blockers and methods for use | TRPV1, ASIC1, TRPA1 | CYP1A2 3384/4885CYP3A4 3440/4885HTR1A 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.