SCHEMBL2580446

SCHEMBL2580446

NC(=S)NCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10788409 0.97 ALDH1A1 (0.37)
SCHEMBL10676425 0.77
SCHEMBL5945918 0.77 ALDH1A1 (0.38)
SCHEMBL13504795 0.75 LOXL2 (0.36)
SCHEMBL18343440 0.75 CA2 (0.34)
SCHEMBL12615004 0.74 GAA (0.38)
SCHEMBL13504796 0.74 LOXL2 (0.31)
SCHEMBL308777 0.72
SCHEMBL5393690 0.72
SCHEMBL13809374 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2934142-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 EP disclosed
US-20170156320-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2017-06-08 US disclosed
US-20170156320-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2017-06-08 US disclosed
US-20160029635-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-02-04 US disclosed
US-20160029635-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-02-04 US disclosed
US-9215870-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2015-12-22 US disclosed
US-9215870-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2015-12-22 US disclosed
US-9210927-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2015-12-15 US disclosed
US-9210927-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2015-12-15 US disclosed
WO-2014120355-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-08-07 WO disclosed
WO-2007028083-A2 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2007-03-08 WO disclosed
US-7101880-B2 Peptidic compounds as cysteine protease inhibitors SCHERING AKTIENGESELLSCHAFT (DE) 2006-09-05 US disclosed
US-20040127426-A1 Peptidic compounds as cysteine protease inhibitors AXYS PHARMACEUTICALS, INC. 2004-07-01 US disclosed
WO-2004000838-A1 PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2003-12-31 WO disclosed
CN-1020061-C Insecticidal and acaricidal agents containing thiadiazines and process for their preparation MITSUI TOATSU CHEMICALS (JP) 1993-03-17 CN disclosed
CN-1039242-A The preparation method of novel thiadiazine and the sterilant and the miticide that contain this type of thiadiazine MITSUI TOATSU CHEMICALS (JP) 1990-01-31 CN disclosed
US-4665073-A HISTAMINE H2-ANTAGONISTS ICI AMERICAS INC. (GB) 1987-05-12 US disclosed
EP-0060094-B1 GUANIDINE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-22 EP disclosed
US-4447441-A ANTIHISTAMINE, ANTIULCER AND ANTISECRETORY AGENT IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-05-08 US disclosed
EP-0060094-A2 Guanidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-15 EP disclosed