SCHEMBL258045

SCHEMBL258045

CCCCCCCCCCCCOCC(O)COS(=O)(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.59
LPAR5 Q9H1C0 1/20 0.58
HTT P42858 1/20 0.57
SPHK1 Q9NYA1 1/20 0.49
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
PLA2G2C Q5R387 3/20 0.43
LPAR1 Q92633 2/20 0.42
LPAR3 Q9UBY5 2/20 0.42
CA1 P00915 7/20 0.42
CA2 P00918 7/20 0.42
CA9 Q16790 6/20 0.42
CA12 O43570 3/20 0.42
CA7 P43166 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA3 P07451 2/20 0.42
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42
CA5A P35218 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258053 1.00 USP2 (0.59) USP2LPAR5HTTSPHK1CYP1A2
SCHEMBL11565852 0.98 USP2 (0.56) USP2LPAR5HTTSPHK1CYP1A2
Methylamine SCHEMBL28907084 0.97 HTT (0.58) USP2LPAR5HTTSPHK1CYP1A2
SCHEMBL13299410 0.88 USP2 (0.54) USP2LPAR5HTTSPHK1CYP1A2
SCHEMBL11565849 0.86 USP2 (0.58) USP2LPAR5HTTSPHK1CYP1A2
SCHEMBL258038 0.84 RECQL (0.59) USP2LPAR5HTTSPHK1CYP1A2
SCHEMBL258049 0.84 RECQL (0.59) USP2LPAR5HTTSPHK1CYP1A2
SCHEMBL258062 0.84 LPAR5 (0.41) USP2LPAR5HTTSPHK1CYP1A2
SCHEMBL9117095 0.84 USP2 (0.80) USP2LPAR5HTTSPHK1CYP1A2
SCHEMBL8527626 0.84 USP2 (0.80) USP2LPAR5HTTSPHK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968607-B2 Cosmetics 1-isostearylglycerol-3-Sulfate Sodium Salt, used for constriction of keratinocytes; aging resistance KOA CORPORATION (JP) 2011-06-28 US disclosed
EP-1325737-B1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS KAO CORP (JP) 2009-12-16 EP disclosed
US-20080234390-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS KAO CORPORATION (JP) 2008-09-25 US disclosed
US-20040009140-A1 Skin pore minimizers and skin elasticity improvers KAO CORPORATION (JP) 2004-01-15 US disclosed
EP-1325737-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS Kao Corporation (JP) 2003-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040009140-A1 Skin pore minimizers and skin elasticity improvers CUTA, DSG1, OGA USP2 2585/4885LPAR5 115/4885HTT 4782/4885
US-20080234390-A1 SKIN PORE MINIMIZERS AND SKIN ELASTICITY IMPROVERS DSG1, CUTA, OGA USP2 2626/4885LPAR5 265/4885HTT 4800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.